Nga tikanga tiaki amino noa
1. Cbz
Benzyloxycarbonyl (Cbz) Amino Parea
Te parenga o N-benzyloxycarbonyl (Cbz)
Reagents whakamahia noa - CbzCl
2. Alloc
Allyloxycarbonyl (Alloc) roopu amino parea
3. Trifluoroacetyl
Trifluoroacetyl parenga amino rōpū
4. Benzyl
p-methoxybenzyl (PMB) parenga amino roopu
2,4-dimethoxybenzyl rōpū amino tiaki
Benzyl tiaki amino
Te whakakore i te roopu amino parea-benzyl
N-Bn debenzylation na roto i te tikanga chloroformate
5. Pht (phthaloyl)
Ko nga roopu amino e tiakina ana a Phthaloyl (Pht).
Ko te whakakore i te roopu amino e tiakina ana e te phthaloyl
6. Benzenesulfonyl
Nitrobenzenesulfonyl parenga amino rōpū
p-toluenesulfonyl (Tos) tiaki amino
7. Trt
Trityl tiaki amino
Te whakakore i te roopu amino kua tiakina e te trityl
8. Boc
Tert-butoxycarbonyl parenga amino roopu
Te whakakore i te N-tert-butoxycarbonyl
Oxalyl Chloride De-Boc
9. Fmoc
Wat methoxycarbonyl parenga roopu amino
Reagents whakamahia noa - Fmoc-Cl
10. SEM
Amino tiaki SEM
11. Ko etahi atu
Acetamide parenga amino roopu
Clauson-Kaas pyrrole synthesis tauhohenga (ka taea te whakamahi i tenei tauhohenga hei tikanga hei tiaki i nga roopu amino, ka taea te whakakapi i te whakamarumaru Boc rua, a ka pai ake)
Reagents whakamahia noa - benzyl (chloromethyl) ether
Reagents whakamahia noa - (chloromethyl) methyl ether [MOMCl]
Tiaki Carbamate
Te wa tuku: Sep-07-2023